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Non-polar solid phase extraction is a type of chromatography that makes use of an adsorbent to draw out a nonpolar analyte. There are a number of techniques for this sort of chromatography, yet the basic concept coincides as regular phase chromatography. In this method, the adsorbent has a solid affinity for the nonpolar analyte, however its interaction with the polar molecules is limited. This makes it valuable for separation of weakly polar analytes. The polar particles are then eluted by a nonpolar solvent.

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